This study aims to interpret literary works from the point of view of hermeneutical, humanistic theory and their relation to the philosophy of science. Hermeneutic theory is used in various sciences. This theory is also used in interdisciplinary studies as a connection with interpretation and philosophy. The philosophy of science itself is a process of freedom to think in depth regarding information that is systematic, theoretical, and can be justified. The subject of this study is in the form of hermeneutic and humanistic theory and philosophy of science. The object of study is Harper Lee’s novel To Kill A Mockingbird. This study is descriptive qualitative. Data were collected through reading and study methods (reading and reviewing) .The form of data is in the form of writing/document. The quotations in the novel To Kill A Mockingbird which correspond to this study are interpreted with values in the Indonesian family from the writer’s perspective as an Indonesian child. This study aims to interpret literary works from the point of view of hermeneutical, humanistic theory, and its relation to the philosophy of science. Hermeneutic theory is used in various sciences. This theory is also used in interdisciplinary studies as a reference for interpretation and philosophy. The philosophy of science itself is a process of thinking in depth regarding information that is systematic, theoretical, and can be justified.